Altered calcium homeostasis: a possible mechanism of aluminium-induced neurotoxicity
نویسندگان
چکیده
منابع مشابه
ANTICONVULSANT THERAPY-INDUCED ALTERATIONS IN CALCIUM HOMEOSTASIS
35 epileptic patients, aged 10 to 58 years (mean 23), who were taking anticonvulsant drugs were studied. The patients exhibited a 34% reduction in serum calcium levels, a 41 % increase in serum alkaline phosphatase activity and a slight but insignificant decrease in serum phosphate, compared to untreated controls. These changes appear to be related to the anticonvulsant drug taken, in the ...
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The aetiology of neurodegenerative diseases (ND) seems to involve susceptibility genes and environmental factors. Toxic metals are considered major environmental pollutants. Following our study of a case of multiple sclerosis (MS) improvement due to removal of aluminium (Al) and other toxic metals, we have examined the possible relationship between Al intoxication and ND. We used the slow intra...
متن کاملanticonvulsant therapy-induced alterations in calcium homeostasis
35 epileptic patients, aged 10 to 58 years (mean 23), who were taking anticonvulsant drugs were studied. the patients exhibited a 34% reduction in serum calcium levels, a 41 % increase in serum alkaline phosphatase activity and a slight but insignificant decrease in serum phosphate, compared to untreated controls. these changes appear to be related to the anticonvulsant drug taken, in the follo...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
سال: 1996
ISSN: 0925-4439
DOI: 10.1016/0925-4439(95)00100-x